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HRID555475

反应详情

EQUATION

反应方程式

HRID 555475 的结构方程式

REACTANTS

反应物

3
反应SMILES：COc1cc(C=O)ccc1O
HCID1183

4-Hydroxy-3-methoxybenzaldehyde

C8H8O3

反应SMILES：COc1cc(N)c(C(N)=O)c(OC)c1
HCID20349016

2-Amino-4,6-dimethoxybenzamide

C9H12N2O3

反应SMILES：COc1cc(OC)c2c(=O)[nH]c(-c3ccccn3)nc2c1
HCID136037998

未命名化合物

PRODUCTS

产物

1
反应SMILES：COc1cc(OC)c2c(=O)[nH]c(-c3ccc(O)c(OC)c3)nc2c1
HCID136037993

未命名化合物

收率 36%

PROCEDURE

实验过程

2-(4-Hydroxy-3-methoxyphenyl)-5,7-dimethoxyquinazolin-4(3H)-one was synthesized from 2-amino-4,6-dimethoxybenzamide and 4-hydroxy-3-methoxybenzaldehyde, using the method described for 5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-one. 2-(4-Hydroxy-3-methoxyphenyl)-5,7-dimethoxyquinazolin-4(3H)-one (90 mg, 36%) was isolated as a white solid. Selected data: MS (m/z): 329.06; MP 294-296° C.