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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 555482Generated: October 29, 2026

Anthranilamide → 2-[4-(4-Oxidanylidene-3h-Quinazolin-2-Yl)phenoxy]ethanoic Acid

https://huagongshe.com/reaction/555482

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnthranilamideHCID 6942—
ReactantAcetic acid, 2-(4-formylphenoxy)-HCID 89177—
Reactant5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-oneHCID 136037998—
Product2-[4-(4-Oxidanylidene-3h-Quinazolin-2-Yl)phenoxy]ethanoic AcidHCID 13556665973%

Reaction Steps

2-(4-(4-Oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetic acid was synthesized from anthranilamide and 4-formyl phenoxy acetic acid, using the method described for 5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-one. 2-(4-(4-Oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetic acid (800 mg, 73%) was isolated as a white solid. Selected data: MS (m/z): 296.98; MP 285-287° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08053440B2
Source datasetuspto-grants-2011_11
ORD IDord-e6ed53072e6b45aa895f04b350d713d2
Source noteuspto-grants-2011_11