HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dimethoxy-6-nitrobenzamide → 2-Amino-4,5-dimethoxybenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dimethoxy-6-nitrobenzamide | HCID 2736193 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Amino-4,5-dimethoxybenzamide | HCID 10867236 | 100.2% |
Reaction Steps
A solution of 4,5-dimethoxy-2-nitrobenzamide (10 g, 44.24 mmol) in MeOH (260 mL) was mixed with palladium/carbon (2 g) and subjected to hydrogenation (50 psi) for 20 h. The reaction mixture was filtered through a Celite pad, concentrated to yield 8.7 g of 2-amino-4,5-dimethoxybenzamide (100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08053440B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-508d559b3b45492d8387e472a549f77f |
| Source note | uspto-grants-2011_11 |