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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 555525Generated: October 31, 2026

HCID 591110, compound → HCID 136037999, compound

https://huagongshe.com/reaction/555525

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 591110HCID 591110—
Reactant2-Amino-4,6-dimethoxybenzamideHCID 20349016—
Reactant5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-oneHCID 136037998—
ProductHCID 136037999HCID 13603799928%

Reaction Steps

5,7-Dimethoxy-2-(4-methoxy-3-(morpholinomethyl)phenyl)quinazolin-4(3H)-one was synthesized from 2-amino-4,6-dimethoxybenzamide and 4-methoxy-3-morpholin-4-ylmethyl-benzaldehyde, using the method described for 5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-one. 5,7-Dimethoxy-2-(4-methoxy-3-(morpholinomethyl)phenyl)quinazolin-4(3H)-one (65 mg, 28%) was isolated as a light yellow solid. Selected data: MS (m/z): 412.07; MP 282.7-284.5° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08053440B2
Source datasetuspto-grants-2011_11
ORD IDord-57cf810d75db4de6809de338514db273
Source noteuspto-grants-2011_11