Benzoic acid, 2,4-dihydroxy-, hydrazide → 2,4-dihydroxy-N'-[1-[1-(4-iodophenyl)-3-methyl-5-oxopyrazol-4-ylidene]ethyl]benzohydrazide

Participants

Reaction Conditions

Reaction Steps

1.03 g (3 mmol) of 1-(5-hydroxy-1-(4-iodophenyl)-3-methyl-1H-pyrazol-4-yl)-ethanone and 505 mg (3 mmol) of 2,4-dihydroxybenzoic hydrazide were dissolved in 50 ml of DMSO and heated at 85° C. for 9 hours with stirring. After cooling and evaporation of the solvent, the crude product was recrystallized from chloroform/ether to give 1.39 g of the desired product as a pale brown solid (yield 94%).

Provenance & Evidence