Methyl 4-(hydrazinecarbonyl)benzoate → HCID 178497999, compound

HRID 555599Notes

Reaction equation

HRID 555599 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([OH:14])=[C:12]([C:15](=O)[CH3:16])[C:11]([CH3:18])=[N:10]2)[CH:5]=[CH:6][C:7]=1[CH3:8].[CH3:19][O:20][C:21]([C:23]1[CH:32]=[CH:31][C:26]([C:27]([NH:29][NH2:30])=[O:28])=[CH:25][CH:24]=1)=[O:22]>>[CH3:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13](=[O:14])[C:12](=[C:15]([NH:30][NH:29][C:27](=[O:28])[C:26]3[CH:25]=[CH:24][C:23]([C:21]([O:20][CH3:19])=[O:22])=[CH:32][CH:31]=3)[CH3:16])[C:11]([CH3:18])=[N:10]2)[CH:5]=[CH:6][C:7]=1[CH3:8]

Participants

3

Reactant 2

HCID 596004Methyl 4-(hydrazinecarbonyl)benzoateHCID 178466978HCID 178466978, compound

Product 1

HCID 178497999HCID 178497999, compound

Procedure

From 1-(1-(3,4-dimethylphenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl)-ethanone and 4-methoxycarbonylbenzhydrazide, 53.0 mg of the desired product was obtained in the same manner as in Synthetic Example 4 as a pale yellow solid (yield 64%).

Sources & evidence

ORD record
ord-400963f839234b5991d9a6f9c3520ae7
Source dataset
uspto-grants-2011_11
Patent number
US08053453B2

Reaction notes

Loading…