Methyl 3-(hydrazinecarbonyl)benzoate → HCID 178497870, compound

HRID 555602Notes

Reaction equation

HRID 555602 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([OH:14])=[C:12]([C:15](=O)[CH3:16])[C:11]([CH3:18])=[N:10]2)[CH:5]=[CH:6][C:7]=1[CH3:8].[CH3:19][O:20][C:21]([C:23]1[CH:24]=[C:25]([CH:30]=[CH:31][CH:32]=1)[C:26]([NH:28][NH2:29])=[O:27])=[O:22]>>[CH3:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13](=[O:14])[C:12](=[C:15]([NH:29][NH:28][C:26](=[O:27])[C:25]3[CH:30]=[CH:31][CH:32]=[C:23]([C:21]([O:20][CH3:19])=[O:22])[CH:24]=3)[CH3:16])[C:11]([CH3:18])=[N:10]2)[CH:5]=[CH:6][C:7]=1[CH3:8]

Participants

3

Reactant 2

HCID 12571330Methyl 3-(hydrazinecarbonyl)benzoateHCID 178466978HCID 178466978, compound

Product 1

HCID 178497870HCID 178497870, compound

Procedure

From 1-(1-(3,4-dimethylphenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl)-ethanone and 3-methoxycarbonylbenzhydrazide, 27.4 mg of the desired product was obtained in the same manner as in Synthetic Example 4 as a pale yellow solid (yield 35%).

Sources & evidence

ORD record
ord-4bba3d67b7f347378c13e7c0f9f22c71
Source dataset
uspto-grants-2011_11
Patent number
US08053453B2

Reaction notes

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