Ethanol → HCID 66987941, compound

Participants

Reaction Steps

To 5,5′-Dimethyl-2′-phenyl-2H,2′H-[3,4′]bipyrazolyl-3′-ol (0.118 g, 0.457 mmol) (Example 25) in ethanol (4 ml) add tert-butyl carbazate (0.120 g, 0.914 mmol). Heat at reflux for 1.5 hours, after which evaporate the ethanol. Chromatography on silica gel, eluting with 50% ethyl acetate/heptane provides 0.101 g of a mixture of positional isomers A and B. Use the mixture for the next step.

Provenance & Evidence