2,2,2-Trifluoroethylhydrazine → HCID 178422855, compound

HRID 555636Notes

Reaction equation

HRID 555636 reaction equation
[C:1]1([N:7]2[C:11](=[O:12])[CH:10]([C:13](=O)[CH2:14][C:15](=O)[CH3:16])[C:9]([CH3:19])=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[F:20][C:21]([F:26])([F:25])[CH2:22][NH:23][NH2:24]>>[CH3:16][C:15]1[CH:14]=[C:13]([C:10]2[C:9]([CH3:19])=[N:8][N:7]([C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)[C:11]=2[OH:12])[N:23]([CH2:22][C:21]([F:26])([F:25])[F:20])[N:24]=1

Participants

3

Reactant 2

HCID 787402,2,2-TrifluoroethylhydrazineHCID 131174131-[1-phenyl-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl]-butane-1,3-dione

Product 1

HCID 178422855HCID 178422855, compound

Procedure

Prepare the title compound from 1-[1-phenyl-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl]-butane-1,3-dione and 2,2,2-trifluoro-ethyl hydrazine (70% in water) according to the procedure of Example 28.

Sources & evidence

ORD record
ord-ef08981744db4fe982788638defabed7
Source dataset
uspto-grants-2011_11
Patent number
US08053458B2

Reaction notes

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