Bromoacetonitrile → HCID 10820984, compound

HRID 555732Notes

Reaction equation

HRID 555732 reaction equation
[CH:1]([N:4]1[CH2:9][CH2:8][NH:7][CH2:6][CH2:5]1)([CH3:3])[CH3:2].Br[CH2:11][C:12]#[N:13]>>[CH:1]([N:4]1[CH2:9][CH2:8][N:7]([CH2:11][C:12]#[N:13])[CH2:6][CH2:5]1)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 11534BromoacetonitrileHCID 780131-Isopropylpiperazine

Product 1

HCID 10820984HCID 10820984, compound

Procedure

The title compound is synthesized by coupling of 1-Isopropyl-piperazine and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a colorless oil; ES-MS: M+=168.1; 1HNMR(DMSO-d6) 3.70 (s, 2H), 2.70-2.40 (m, 9H), 0.95 (d, 6H).

Sources & evidence

ORD record
ord-de734d3f8dd04dbf920a70094389af8b
Source dataset
uspto-grants-2011_11
Patent number
US08053457B2

Reaction notes

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