Bromoacetonitrile → HCID 60705380, compound

HRID 555733Notes

Reaction equation

HRID 555733 reaction equation
[CH3:1][N:2]([CH3:11])[CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][NH:8][CH2:7][CH2:6]1.Br[CH2:13][C:14]#[N:15]>>[CH3:1][N:2]([CH3:11])[CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][N:8]([CH2:13][C:14]#[N:15])[CH2:7][CH2:6]1

Participants

3

Reactant 2

HCID 11534BromoacetonitrileHCID 27362291-(2-(Dimethylamino)ethyl)piperazine

Product 1

HCID 60705380HCID 60705380, compound

Procedure

The title compound is synthesized by coupling of Dimethyl-(2-piperazin-1-yl-ethyl)-amine (commercially available from CHESS GmbH) and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a colorless oil; ES-MS: M+=197.2.

Workup

  1. customanalogously to the preparation of Intermediate 149.2 as a colorless oil

Sources & evidence

ORD record
ord-7d82388803474f048035d9f21011d012
Source dataset
uspto-grants-2011_11
Patent number
US08053457B2

Reaction notes

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