HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromoacetonitrile → [4-(2-Pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromoacetonitrile | HCID 11534 | — |
| Reactant | 1-[2-(Pyrrolidin-1-yl)ethyl]piperazine | HCID 2737250 | — |
| Product | [4-(2-Pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-acetonitrile | HCID 86641786 | — |
Reaction Steps
The title compound is synthesized by coupling of 1-(2-Pyrrolidin-1-yl-ethyl)-piperazine (commercially available from ABCR GmbH) and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a colorless solid; ES-MS: M+H=223.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08053457B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-aa9b629df78b41f2b1ce2a53e27f35f5 |
| Source note | uspto-grants-2011_11 |