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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 555738Generated: October 25, 2026

1-Phenylpiperazine → 2-(4-Phenylpiperazin-1-yl)acetonitrile

https://huagongshe.com/reaction/555738

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-PhenylpiperazineHCID 7096—
ReactantBromoacetonitrileHCID 11534—
Product2-(4-Phenylpiperazin-1-yl)acetonitrileHCID 437238—

Reaction Steps

The title compound is synthesized by coupling of 1-Phenyl-piperazine and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a white solid; ES-MS: M+=202.2: AtRet=1.95.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08053457B2
Source datasetuspto-grants-2011_11
ORD IDord-6946c533cda84dd7b1df6f88598e6912
Source noteuspto-grants-2011_11