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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 555749Generated: October 25, 2026

Bromoacetonitrile → [4-(Tetrahydro-furan-2-ylmethyl)-piperazin-1-yl]-acetonitrile

https://huagongshe.com/reaction/555749

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromoacetonitrileHCID 11534—
Reactant1-(Tetrahydro-2-furylmethyl)piperazineHCID 2737265—
Product[4-(Tetrahydro-furan-2-ylmethyl)-piperazin-1-yl]-acetonitrileHCID 55027705—

Reaction Steps

The title compound is synthesized by coupling of 1-(Tetrahydro-furan-2-ylmethyl)-piperazine (commercially available from CHESS GmbH) and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a white solid; ES-MS: M+=210.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08053457B2
Source datasetuspto-grants-2011_11
ORD IDord-0b66656f762549f08b7de371a7c9b6db
Source noteuspto-grants-2011_11