HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromoacetonitrile → 2-(4-Benzylpiperidin-1-yl)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromoacetonitrile | HCID 11534 | — |
| Reactant | 4-Benzylpiperidine | HCID 31738 | — |
| Product | 2-(4-Benzylpiperidin-1-yl)acetonitrile | HCID 10680164 | — |
Reaction Steps
The title compound is synthesized by coupling of 4-Benzyl-piperidine and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a colorless oil; ES-MS: M+=215.2: AtRet=2.90.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08053457B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-3e069f62b67546579bcf890c86dc2e52 |
| Source note | uspto-grants-2011_11 |