HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromoacetonitrile → (4-Phenoxy-piperidin-1-yl)-acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromoacetonitrile | HCID 11534 | — |
| Reactant | 4-Phenoxypiperidine | HCID 18878 | — |
| Product | (4-Phenoxy-piperidin-1-yl)-acetonitrile | HCID 47544198 | — |
Reaction Steps
The title compound is synthesized by coupling of 4-Phenoxy-piperidine (commercially available from Alfa Aesar) and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a colorless oil; ES-MS: M+H=217.2: CtRet=4.80.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08053457B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-2fb9c0bc3e42484fbb7f0aa9aff7a98b |
| Source note | uspto-grants-2011_11 |