HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromoacetonitrile → [4-(2-Ethoxy-ethyl)-piperazin-1-yl]-acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromoacetonitrile | HCID 11534 | — |
| Reactant | 1-(2-Ethoxyethyl)piperazine | HCID 2734643 | — |
| Product | [4-(2-Ethoxy-ethyl)-piperazin-1-yl]-acetonitrile | HCID 63336683 | — |
Reaction Steps
The title compound is synthesized by coupling of 4-(2-Ethoxy-ethyl)-piperazine (commercially available from ABCR GmbH) and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a colorless oil; ES-MS: M+H=198.2; 1HNMR(DMSO-d6) 3.70 (s, 2H), 3.45 (q, 2H), 3.40 (q, 2H), 2.40-2.30 (m, 10H), 1.05 (t, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08053457B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-50ac3cb6e71e44babcad2700b39d0b9f |
| Source note | uspto-grants-2011_11 |