Boron tribromide → HCID 57991641, compound

Participants

Reaction Steps

A procedure similar to that in Example 7 was used. 3,4-dimethoxy-N-[4-(4-methoxy-phenyl)-5-methyl-thiazol-2-yl]-benzamide prepared in Example 54 and boron tribromide were used as starting materials. The obtained crude product was recrystallized with acetone to give a product as a white solid in a yield of 61.2%, mp: 285└(Dec.). 1H-NMR (CD3OD, 400 MHz) δ: 2.46 (3H, s, ArCH3), 6.88˜6.98 (3H, m, ArH), 7.40˜7.51 (4H, m, ArH); EI-MS m/e (%): 342.1 (M+, 29), 206.2 (100), 137.1 (36); HREI-MS Calcd. for C17H14N2O4S: 342.0674. found: 342.0670.

Provenance & Evidence