HCID 57394089, compound → Caprazene

Participants

Reaction Conditions

Reaction Steps

The reaction of Step (1) is as shown below. Specifically, 200 mg of caprazamycin B were dissolved in 6 mL of 80% aqueous acetic acid and the resulting solution was heated at 70° C. for 2 hours. Subsequently, the reaction mixture was concentrated and acetone was added to the syrup-like concentrate. The resulting precipitate was collected by filtration, washed with acetone and dried to afford 96.3 mg of caprazene as a colorless solid (99% yield).

Provenance & Evidence