反应详情

A mixture of (+)-pinanediol (23.9 g, 0.140 mol) and 2-methylpropylboronic acid (15 g, 0.147 mol) in diethyl ether (300 ml) was stirred at room temperature for 24 h. The mixture was dried over anhydrous sodium sulfate and purified by column chromatography (Silica gel 230-400 mesh), eluting with hexane:ethyl acetate 90:10 mixture. The product was obtained as a clear oil (32.6 g, 94% yield).

1. dry with materialThe mixture was dried over anhydrous sodium sulfate
2. custompurified by column chromatography (Silica gel 230-400 mesh)
3. washeluting with hexane:ethyl acetate 90:10 mixture