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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 556325Generated: October 29, 2026

Hydrochloric Acid → HCID 59496138, compound

https://huagongshe.com/reaction/556325

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthyl AcetateHCID 8857—
ReactantHCID 59496140HCID 59496140—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 59496138HCID 59496138—

Reaction Steps

4 M of Hydrogen chloride in 1,4-dioxane (0.8 mL) was added to [5-Methyl-3-(3-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-2-yl]-carbamic acid tert-butyl ester (compound r, 0.14 g, 0.00036 mol). The mixture was stirred at room temperature for 2 hours. Solvent evaporated to give 0.1 g as a yellow oil. Rf 0.42, 100% ethyl acetate; MS m/z 292 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08058274B2
Source datasetuspto-grants-2011_11
ORD IDord-90c7609d5c42455491bab9664cb2eff4
Source noteuspto-grants-2011_11