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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 556548생성일: 2026년 10월 25일

2-Fluorophenylboronic acid → 4-Sec-butylamino-6-(2-fluoro-phenyl)-2-methylsulfanyl-pyrimidine-5-carbaldehyde

https://huagongshe.com/reaction/556548

반응식

참여 물질

역할이름HCID투입량
반응물2-Fluorophenylboronic acidHCID 2734354—
반응물4-Sec-butylamino-6-chloro-2-methylsulfanyl-pyrimidine-5-carbaldehydeHCID 59639584—
생성물4-Sec-butylamino-6-(2-fluoro-phenyl)-2-methylsulfanyl-pyrimidine-5-carbaldehydeHCID 59639535—

반응 단계

Prepared as described above in Example 11 starting from 4-sec-butylamino-6-chloro-2-methylsulfanyl-pyrimidine-5-carbaldehyde and 2-fluorophenylboronic acid to give the title compound 4-sec-butylamino-6-(2-fluoro-phenyl)-2-methylsulfanyl-pyrimidine-5-carbaldehyde. 1H-NMR: δ 0.96 (m, 3H), 1.30 (m, 3H), 1.67 (m, 2H), 2.58 (s, 3H), 4.38 (m, 1H), 7.11-7.31 (m, 2H), 7.42-7.58 (m, 2H), 9.07 (br s, 1H), 9.63 (s, 1H). LC MS (m/e)=306 (MH+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08058282B2
출처 데이터셋uspto-grants-2011_11
ORD IDord-1ae60e2b4b334b97917ed85682165315
출처 메모uspto-grants-2011_11