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HRID556558

反应详情

EQUATION

反应方程式

HRID 556558 的结构方程式

REACTANTS

反应物

2
结构：NC(CO)CO
HCID68294

1,3-Propanediol, 2-amino-

C3H9NO2

结构：CS(=O)(=O)c1nc(-c2ccccc2Cl)c2ccc(=O)n(-c3ccccc3Cl)c2n1
HCID10225578

未命名化合物

PRODUCTS

生成物

1
结构：O=c1ccc2c(-c3ccccc3Cl)nc(NC(CO)CO)nc2n1-c1ccccc1Cl
HCID10298043

未命名化合物

PROCEDURE

实验过程

The product of Example 47, and serinol were reacted by the procedure of Example 60 to afford the title compound 4,8-bis-(2-chloro-phenyl)-2-(2-hydroxy-1-hydroxymethyl-ethylamino)-8H-pyrido[2,3-d]pyrimidin-7-one. 1H-NMR (CDCl3) δ 3.44 (m, 1H), 3.68 (m, 4H), 6.30 (br s, 1H), 6.48 (d, 1H, J=9.7 Hz), 7.24-7.65 (m, 9H). LC MS (m/e)=457 (MH+).