HCID 66758567, compound → 4-(4-Chlorophenyl)-1-[3-(5,11-dihydro-7-dimethylaminocarbonyl[1]benzoxepino[2,3-b]pyridin-5-ylidene)propyl]piperidin-4-ol

HRID 556912Notes

Reaction equation

HRID 556912 reaction equation
C(COC1C2CC(=CCCN3CCC(C4C=CC(Cl)=CC=4)(O)CC3)C3[C:15](OC=2C=CC=1)=[N:16][CH:17]=CC=3)(O)=O.[C:38]([C:41]1[C:46]2[CH2:47][C:48](=[CH:56][CH2:57][CH2:58][N:59]3[CH2:64][CH2:63][C:62]([C:66]4[CH:71]=[CH:70][C:69]([Cl:72])=[CH:68][CH:67]=4)([OH:65])[CH2:61][CH2:60]3)[C:49]3[C:50]([O:55][C:45]=2[CH:44]=[CH:43][CH:42]=1)=[N:51][CH:52]=[CH:53][CH:54]=3)(O)=[O:39]>>[Cl:72][C:69]1[CH:68]=[CH:67][C:66]([C:62]2([OH:65])[CH2:61][CH2:60][N:59]([CH2:58][CH2:57][CH:56]=[C:48]3[C:49]4[C:50](=[N:51][CH:52]=[CH:53][CH:54]=4)[O:55][C:45]4[CH:44]=[CH:43][CH:42]=[C:41]([C:38]([N:16]([CH3:17])[CH3:15])=[O:39])[C:46]=4[CH2:47]3)[CH2:64][CH2:63]2)=[CH:71][CH:70]=1

Participants

3

Reactant 2

HCID 66758567HCID 66758567, compoundHCID 667586701-[3-(7-Carboxy-5,11-dihydro[1]benzoxepino[2,3-b]pyridin-5-ylidene)propyl]-4-(4-chlorophenyl)piperidin-4-ol

Product 1

HCID 667580144-(4-Chlorophenyl)-1-[3-(5,11-dihydro-7-dimethylaminocarbonyl[1]benzoxepino[2,3-b]pyridin-5-ylidene)propyl]piperidin-4-ol

Procedure

The titled compound was prepared by following the procedure of example 134, but replacing the product of example 133 with the product of example 118.

Sources & evidence

ORD record
ord-bec27e6f7b1e4fe2942988f84910d96f
Source dataset
uspto-grants-2011_11
Patent number
US08058287B2

Reaction notes

Loading…