HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphosgene → 5,6-Dimethoxyisatoic anhydride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphosgene | HCID 94429 | — |
| Reactant | 6-Amino-2,3-dimethoxybenzoic acid | HCID 11745590 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 5,6-Dimethoxyisatoic anhydride | HCID 12762380 | — |
Reaction Steps
10.0 g (50.7 mmol) 6-Amino-2,3-dimethoxy-benzoic acid were dissolved in 150 ml tetrahydrofuran, 6.52 g (22.0 mmol) triphosgene were added and the solution was refluxed for 3 h. After pouring on 400 ml of a ice/water mixture the precipitate was filtrated and rinsed with water and methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08058431B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-7c2639eeec404c40a486bcc56b86cecf |
| Source note | uspto-grants-2011_11 |