HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 86597618, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Ammonium Acetate | HCID 517165 | — |
| Reactant | HCID 17985442 | HCID 17985442 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86597618 | HCID 86597618 | 42% |
Reaction Steps
Combine 7-(hydroxymethyl)furo[3,2-c]pyran-4-one (8.28 g, 49.8 mmol), ammonium acetate (76.8 g, 996 mmol), and glacial acetic acid and heat at reflux for 3.5 hours. Cooling to room temperature, pouring into ethylacetate, washing with water saturated aqueous sodium bicarbonate, and brine, drying over magnesium sulfate, filtering and concentrating gives 4.42 g (42%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08058425B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-c55e5311d4b0470c8542360b0a8f1f05 |
| Source note | uspto-grants-2011_11 |