反应详情

To a solution of tert-butyl alcohol (650 mL) and di-tert-butyl carbonate (24 g) was added 2-Aminopyridine (9.4 g) slowly. This mixture was stirred at room temperature for 24 hours. This reaction solution was concentrated under a reduced pressure, and the residue thereof was purified by silica gel column chromatography (heptane:ethyl acetate=1:1) to obtain the title compound (18 g).

1. concentrationThis reaction solution was concentrated under a reduced pressure
2. customthe residue thereof was purified by silica gel column chromatography (heptane:ethyl acetate=1:1)