p-Toluenesulfonic acid → HCID 25071083, compound

Participants

Reaction Steps

3-(3-(4-(Pyridin-2-yloxymethyl)-benzyl)-isoxazol-5-yl)-pyridin-2-yl amine (100 mg) was dissolved in methanol (5 mL), and p-toluenesulfonic acid (55.7 mg) was added thereto. This mixture was stirred at room temperature for 5 minutes, and then, concentrated in vacuo. To the residue was added ethanol (5 mL), and subjected to ultrasound treatment to cause solids to be precipitated. This solids were filtered, washed with ethanol and then dried in vacuo to obtain the title compound (117 mg).

Provenance & Evidence