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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 557307Generated: October 25, 2026

Allylmorpholine → N-[3-(3-Morpholin-4-yl-propyl)-5-trifluoromethyl-phenyl]-acetamide

https://huagongshe.com/reaction/557307

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAllylmorpholineHCID 136522—
ReactantN-[3-bromo-5-(trifluoromethyl)phenyl]acetamideHCID 21959349—
ReactantN-[3-(3-Piperidin-1-yl-propyl)-5-trifluoromethyl-phenyl]-acetamideHCID 21959446—
ProductN-[3-(3-Morpholin-4-yl-propyl)-5-trifluoromethyl-phenyl]-acetamideHCID 21959489—

Reaction Steps

N-[3-(3-Morpholin-4-yl-propyl)-5-trifluoromethyl-phenyl]-acetamide was prepared from allyl morpholine and N-(3-bromo-5-trifluoromethyl-phenyl)-acetamide similar to that described in the preparation of N-[3-(3-piperidin-1-yl-propyl)-5-trifluoromethyl-phenyl]-acetamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08058445B2
Source datasetuspto-grants-2011_11
ORD IDord-4a4eeaff391847f1819109b4217f2113
Source noteuspto-grants-2011_11