HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine, 1-methyl,4-methylene- → N-[3-(1-Methylpiperidin-4-yl)-5-trifluoromethyl-phenyl]-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine, 1-methyl,4-methylene- | HCID 139537 | — |
| Reactant | N-[3-bromo-5-(trifluoromethyl)phenyl]acetamide | HCID 21959349 | — |
| Reactant | N-[3-(3-Piperidin-1-yl-propyl)-5-trifluoromethyl-phenyl]-acetamide | HCID 21959446 | — |
| Product | N-[3-(1-Methylpiperidin-4-yl)-5-trifluoromethyl-phenyl]-acetamide | HCID 21959571 | — |
Reaction Steps
N-[3-(1-Methylpiperidin-4-yl)-5-trifluoromethyl-phenyl]-acetamide was prepared from 1-methyl-4-methylene-piperidine and N-(3-bromo-5-trifluoromethyl-phenyl)-acetamide similar to that described in the preparation of N-[3-(3-piperidin-1-yl-propyl)-5-trifluoromethyl-phenyl]-acetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08058445B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-1c14886fc4264f4fa77a069917eff155 |
| Source note | uspto-grants-2011_11 |