Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 557318Generated: October 31, 2026

1-Tert-butyl 4-ethyl piperidine-1,4-dicarboxylate → Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/557318

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Tert-butyl 4-ethyl piperidine-1,4-dicarboxylateHCID 2758812—
Reactant2-morpholin-4-ylpropan-1-olHCID 10986371—
ProductTert-butyl 4-(hydroxymethyl)piperidine-1-carboxylateHCID 2764081—

Reaction Steps

1-Boc-4-Hydroxymethyl-piperidine was prepared from 1-Boc-piperidine-4-carboxylic acid ethyl ester by a procedure similar to that described in the preparation of 2-morpholin-4-yl-propanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08058445B2
Source datasetuspto-grants-2011_11
ORD IDord-298adbb55eaf4935a7d2b462dccff480
Source noteuspto-grants-2011_11