Ammonium Chloride → HCID 10270834, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of N-[4-(tert-butyl)-3-nitrophenyl]{2-[(2-pyridylmethyl)amino](3-pyridyl)}carboxamide (100 mg, 0.25 mmol, Example 73), iron powder (69 mg, 1.25 mmol) and NH4Cl (10 mg, 0.17 mmol) in EtOH (0.5 mL) and H2O (0.5 ml) was stirred for 4 h at 80° C. The reaction mixture was filtered, concentrated, and purified through column chromatography to give the product. MS (ES+):376 M+H); (ES−):374(M−H). Calc'd. for C22H25N5O−375.21.

Provenance & Evidence