Acetic Acid → HCID 15979087, compound

Participants

Reaction Steps

100 mg (0.53 mmol) of 2-methyl-4-oxo-4H-chromene-8-carbaldehyde are dissolved with 61.7 mg (0.53 mmol) of methyl 3-oxobutanoate, 43.6 mg (0.53 mmol) of 3-aminocrotononitrile and 31.9 mg (0.53 mmol) of acetic acid in 5 ml of 2-propanol and heated under reflux under argon for 4 h. After cooling to room temperature, the crystallized product is filtered off and washed with 2-propanol and, diethyl ether. 97 mg (52% of theory) of the title compound are obtained as a yellow solid.

Provenance & Evidence