Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | Mesityl oxide | HCID 8858 | — |
| Reactant | tert-Butyl (4-aminophenyl)carbamate | HCID 688611 | — |
| Product | HCID 11392086 | HCID 11392086 | — |
Reaction Steps
A mixture of N-Boc-1,4-phenylenediamine (5.0 g) and iodine (1.3 g) in mesityl oxide (25 ml) was stirred at 100° C. for 2 h. The reaction mixture was concentrated in vacuo and the residue was chromatographed on Al2O3 (Alumina B, act. III) in heptane/dichloromethane=8/2 as eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08058441B2 |
|---|
| Source dataset | uspto-grants-2011_11 |
|---|
| ORD ID | ord-df9c2ba4eadf41e1ae8c024e3d8a917d |
|---|
| Source note | uspto-grants-2011_11 |
|---|
