HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → HCID 17962900, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | Cesium fluoride | HCID 25953 | — |
| Reactant | Phenylboronic Acid | HCID 66827 | — |
| Reactant | 1-Acetyl-4-phenyl-6-(2-bromo-3-methylbenzoyl)amino-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline | HCID 17962903 | — |
| Catalyst | Bis(dibenzylideneacetone)palladium | HCID 9811564 | — |
| Solvent | Dimethoxyethane ethanol | HCID 20074477 | — |
| Product | HCID 17962900 | HCID 17962900 | — |
Reaction Steps
Suzuki cross-coupling of 1-acetyl-4-phenyl-6-(2-bromo-3-methylbenzoyl)amino-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline (16 mg), benzeneboronic acid (25 mg), cesium fluoride (21 mg), triphenylphosphine (7.0 mg) and tris(dibenzylideneacetone)dipalladium(0) (6.0 mg) in dimethoxyethane/ethanol 4:1 (v/v) (5 ml) was performed according to the method described in example 13.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08058441B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-06ae49d6334a414d867796548954fd5f |
| Source note | uspto-grants-2011_11 |