HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylmethanesulfonyl chloride → HCID 11431176, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylmethanesulfonyl chloride | HCID 74740 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 1-(6-amino-2,2,4-trimethyl-4-phenyl-3,4-dihydroquinolin-1(2H)-yl)ethanone | HCID 2837084 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 11431176 | HCID 11431176 | — |
Reaction Steps
Sulfonylation of 1-acetyl-6-amino-4-phenyl-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline (10 mg) with α-toluenesulfonyl chloride (12 mg) and N,N-diisopropylethylamine (22 μl) in tetrahydrofuran (25 ml) was performed according to the acylation method described in example 6.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08058441B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-ed9e67a5898a4e20b508051051ea3d9c |
| Source note | uspto-grants-2011_11 |