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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 55761Generated: October 30, 2026

O-Methylthreonine → (2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acid

https://huagongshe.com/reaction/55761

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-MethylthreonineHCID 2724875—
Reactant(2S)-2-((methoxycarbonyl)amino)-3-methylbutanoic acidHCID 10942966—
Product(2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acidHCID 59540170—

Reaction Steps

(2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acid was synthesized similar to N-methoxycarbonyl-L-Valine, using O-Methyl-L-Threonine instead of L-Valine. Dichloromethane extraction was carried out 10 times instead of 3 times.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09433609B2
Source datasetuspto-grants-2016_09
ORD IDord-e9dd720bfda14c73a594adfff2a0b27a
Source noteuspto-grants-2016_09