HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 557632Generated: October 30, 2026
Water → 1-(4-Bromophenyl)cyclopropane-1-carboxylic acid
https://huagongshe.com/reaction/557632
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 1-(4-Bromophenyl)Cyclopropanecarbonitrile | HCID 2795273 | — |
| Solvent | Ethylene Glycol | HCID 174 | — |
| Product | 1-(4-Bromophenyl)cyclopropane-1-carboxylic acid | HCID 16227966 | — |
Reaction Steps
1-(4-Bromo-phenyl)-cyclopropanecarbonitrile (5 g, 22.5 mmol) and potassium hydroxide (5 g, 89.3 mmol) were combined in ethylene glycol (70 mL), and the reaction was stirred at 180° C. for 4 hours. The mixture was poured into H2O, acidified, and filtered to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08058300B2 |
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| Source dataset | uspto-grants-2011_11 |
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| ORD ID | ord-ac8186fc3a044c54a11d156b5ede2911 |
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| Source note | uspto-grants-2011_11 |
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