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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 557632Generated: October 30, 2026

Water → 1-(4-Bromophenyl)cyclopropane-1-carboxylic acid

https://huagongshe.com/reaction/557632

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantPotassium HydroxideHCID 14797—
Reactant1-(4-Bromophenyl)CyclopropanecarbonitrileHCID 2795273—
SolventEthylene GlycolHCID 174—
Product1-(4-Bromophenyl)cyclopropane-1-carboxylic acidHCID 16227966—

Reaction Conditions

Temperature180 °C

Reaction Steps

1-(4-Bromo-phenyl)-cyclopropanecarbonitrile (5 g, 22.5 mmol) and potassium hydroxide (5 g, 89.3 mmol) were combined in ethylene glycol (70 mL), and the reaction was stirred at 180° C. for 4 hours. The mixture was poured into H2O, acidified, and filtered to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08058300B2
Source datasetuspto-grants-2011_11
ORD IDord-ac8186fc3a044c54a11d156b5ede2911
Source noteuspto-grants-2011_11