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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 557658Generated: October 30, 2026

Ethyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylate → 5-(4'-(1-(Ethoxycarbonyl)cyclopropyl)biphenyl-4-yl)-3-methylisoxazole-4-carboxylic acid

https://huagongshe.com/reaction/557658

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylateHCID 53217182—
Reactant5-(4-Bromophenyl)-3-methyl-1,2-oxazole-4-carboxylic acidHCID 56604559—
Product5-(4'-(1-(Ethoxycarbonyl)cyclopropyl)biphenyl-4-yl)-3-methylisoxazole-4-carboxylic acidHCID 66660277—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 6 using 5-(4-bromo-phenyl)-3-methyl-isoxazole-4-carboxylic acid and 1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclopropanecarboxylic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08058300B2
Source datasetuspto-grants-2011_11
ORD IDord-8248eac29d8e41a991b7907b790413b9
Source noteuspto-grants-2011_11