Sodium borohydride → HCID 66660384, compound

HRID 557664Notes

Reaction equation

HRID 557664 reaction equation
[C:1]([Si:5]([CH3:17])([CH3:16])[O:6][C:7]1[CH:8]=[C:9]([C:13](=[O:15])[CH3:14])[CH:10]=[CH:11][CH:12]=1)([CH3:4])([CH3:3])[CH3:2].[BH4-].[Na+]>CO>[C:1]([Si:5]([CH3:17])([CH3:16])[O:6][C:7]1[CH:8]=[C:9]([CH:13]([OH:15])[CH3:14])[CH:10]=[CH:11][CH:12]=1)([CH3:2])([CH3:4])[CH3:3]

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 143614891-(3-{[tert-Butyl(dimethyl)silyl]oxy}phenyl)ethan-1-one

Product 1

HCID 66660384HCID 66660384, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1-[3-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-ethanone (3.67 mmol) in MeOH (5 mL) was treated with sodium borohydride (0.139 g, 3.67 mmol). The reaction was stirred for 20 minutes, and then standard work-up provided the title compound.

Sources & evidence

ORD record
ord-69eec182978c4d04ab96c4ba75fef437
Source dataset
uspto-grants-2011_11
Patent number
US08058300B2

Reaction notes

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