HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → Methyl 3-(pyrrolidin-3-YL)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | methyl 3-[1-(phenoxyacetyl)-2,3-dihydro-1H-pyrrol-3-yl]benzoate | HCID 66662462 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | Methyl 3-(pyrrolidin-3-YL)benzoate | HCID 66661431 | — |
Reaction Steps
To a solution of methyl 3-[1-(phenoxyacetyl)-2,3-dihydro-1H-pyrrol-3-yl]benzoate (0.5 g, 0.001 mol) in methanol (15 mL, 0.37 mol) was added 10% Pd/C (80 mg), and the resulting suspension was stirred under 1 atm of H, (balloon) for 5 h. The mixture was filtered and the filtrate was concentrated to afford the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08058288B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-2b9ad48c26b742e192e596e6b4d45273 |
| Source note | uspto-grants-2011_11 |