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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 557940Generated: October 30, 2026

Methanol → Methyl 3-(pyrrolidin-3-YL)benzoate

https://huagongshe.com/reaction/557940

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
Reactantmethyl 3-[1-(phenoxyacetyl)-2,3-dihydro-1H-pyrrol-3-yl]benzoateHCID 66662462—
CatalystPalladiumHCID 23938—
ProductMethyl 3-(pyrrolidin-3-YL)benzoateHCID 66661431—

Reaction Steps

To a solution of methyl 3-[1-(phenoxyacetyl)-2,3-dihydro-1H-pyrrol-3-yl]benzoate (0.5 g, 0.001 mol) in methanol (15 mL, 0.37 mol) was added 10% Pd/C (80 mg), and the resulting suspension was stirred under 1 atm of H, (balloon) for 5 h. The mixture was filtered and the filtrate was concentrated to afford the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08058288B2
Source datasetuspto-grants-2011_11
ORD IDord-2b9ad48c26b742e192e596e6b4d45273
Source noteuspto-grants-2011_11