Cyclopropylamine → HCID 24995223, compound

Participants

Reaction Conditions

Reaction Steps

To 5-(2-(2-fluoropyridin-4-yl) methylthiophenyl)-N-phenyl-1,3,4-oxadiazol-2-amine (80 mg, 0.19 mmol; Compound 1-(48)) was added cyclopropylamine (200 μL) at room temperature and then the mixture was stirred at 150° C. for 2 hours. The reaction solution was concentrated under a reduced pressure and the residue was purified with a silica gel column chromatography (hexane/ethyl acetate) and to give 5.0 mg (6%) of the titled compound as a colorless solid.

Provenance & Evidence