1-Bromo-2-Chloroethane → 4-(2-chloroethoxy)-3-N-(4-chlorophenyl)-isophthalamide
Reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9](=[O:21])[C:10]2[CH:11]=[C:12]([CH:16]=[CH:17][C:18]=2[O:19][CH3:20])[C:13]([NH2:15])=[O:14])=[CH:4][CH:3]=1.BrC[CH2:24][Cl:25]>>[Cl:25][CH2:24][CH2:20][O:19][C:18]1[CH:17]=[CH:16][C:12]([C:13]([NH2:15])=[O:14])=[CH:11][C:10]=1[C:9]([NH:8][C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=1)=[O:21]Participants
3
Procedure
The captioned compound was synthesized from 3-N-(4-chlorophenyl)-4-methoxyisophthalamide and 1-bromo-2-chloroethane by the same procedure as in the manufacturing method described in Example 1-1-2.
Sources & evidence
- ORD record
- ord-053c55562ce645d881f303b3dfdaca6a
- Source dataset
- uspto-grants-2011_11
- Patent number
- US08063046B2
Reaction notes
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