3-Chloroaniline → 3-N-(3-chlorophenyl)-4-methoxy-isophthalamide

HRID 558363Notes

Reaction equation

[CH3:1][O:2][C:3]1[C:8]([C:9]([OH:11])=O)=[CH:7][C:6]([C:12]([NH2:14])=[O:13])=[CH:5][CH:4]=1.[Cl:15][C:16]1[CH:17]=[C:18]([CH:20]=[CH:21][CH:22]=1)[NH2:19]>>[Cl:15][C:16]1[CH:17]=[C:18]([NH:19][C:9](=[O:11])[C:8]2[CH:7]=[C:6]([CH:5]=[CH:4][C:3]=2[O:2][CH3:1])[C:12]([NH2:14])=[O:13])[CH:20]=[CH:21][CH:22]=1

Participants

Reactant 2

HCID 79323-Chloroaniline

HCID 132228085-Carbamoyl-2-methoxybenzoic acid

Product 1

HCID 592650963-N-(3-chlorophenyl)-4-methoxy-isophthalamide

Procedure

The captioned compound was synthesized from 6-methoxyisophthalamic acid and 3-chloroaniline by the same procedure as in the manufacturing method described in step C of Example 1-3-1.

Sources & evidence

ORD record: ord-1b88656dc69544d4a8014f6b3650db4c
Source dataset: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08063046B2

Reaction notes

Loading…