2-Bromo-4-(trifluoromethoxy)aniline → HCID 59265093, compound

HRID 558383Notes

Reaction equation

HRID 558383 reaction equation
[CH3:1][O:2][C:3]1[C:8]([C:9]([OH:11])=O)=[CH:7][C:6]([C:12]([NH2:14])=[O:13])=[CH:5][CH:4]=1.[Br:15][C:16]1[CH:22]=[C:21]([O:23][C:24]([F:27])([F:26])[F:25])[CH:20]=[CH:19][C:17]=1[NH2:18]>>[Br:15][C:16]1[CH:22]=[C:21]([O:23][C:24]([F:26])([F:27])[F:25])[CH:20]=[CH:19][C:17]=1[NH:18][C:9](=[O:11])[C:8]1[CH:7]=[C:6]([CH:5]=[CH:4][C:3]=1[O:2][CH3:1])[C:12]([NH2:14])=[O:13]

Participants

3

Reactant 2

HCID 6882962-Bromo-4-(trifluoromethoxy)anilineHCID 132228085-Carbamoyl-2-methoxybenzoic acid

Product 1

HCID 59265093HCID 59265093, compound

Procedure

The captioned compound was synthesized from 6-methoxyisophthalamic acid and 2-bromo-4-trifluoromethoxyaniline by the same procedure as in the manufacturing method described in step C of Example 1-3-1.

Sources & evidence

ORD record
ord-53a5cf967afd4a84ae045efd8bfd4f35
Source dataset
uspto-grants-2011_11
Patent number
US08063046B2

Reaction notes

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