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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 558390Generated: October 27, 2026

Methylamine hydrochloride → 4-methoxy-N-methyl-3-[(E)-2-(4-trifluoromethoxyphenyl)-vinyl]-benzamide

https://huagongshe.com/reaction/558390

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamine hydrochlorideHCID 6364545—
Reactant4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acidHCID 23141498—
Product4-methoxy-N-methyl-3-[(E)-2-(4-trifluoromethoxyphenyl)-vinyl]-benzamideHCID 23141522—

Reaction Steps

The captioned compound was synthesized from 4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acid obtained in step B of Example 2-2-1 and methylamine hydrochloride in accordance with the same procedure as in the methods described in step C of Example 1-2-3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063046B2
Source datasetuspto-grants-2011_11
ORD IDord-c1222926fbf84666864c593bf979b03e
Source noteuspto-grants-2011_11