2-Butanamine, 1-methoxy- → 3-[(E)-2-(4-chlorophenyl)-vinyl]-4-methoxy-N-(1-methoxymethyl-propyl)-benzamide

HRID 558399Notes

Reaction equation

HRID 558399 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]2[CH:11]=[C:12]([CH:16]=[CH:17][C:18]=2[O:19][CH3:20])[C:13]([OH:15])=O)=[CH:4][CH:3]=1.[NH2:21][CH:22]([CH2:26][CH3:27])[CH2:23][O:24][CH3:25]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5](/[CH:8]=[CH:9]/[C:10]2[CH:11]=[C:12]([CH:16]=[CH:17][C:18]=2[O:19][CH3:20])[C:13]([NH:21][CH:22]([CH2:23][O:24][CH3:25])[CH2:26][CH3:27])=[O:15])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 938372-Butanamine, 1-methoxy-HCID 231413873-[(E)-2-(4-chlorophenyl)vinyl]-4-methoxy-benzoic acid

Product 1

HCID 231414213-[(E)-2-(4-chlorophenyl)-vinyl]-4-methoxy-N-(1-methoxymethyl-propyl)-benzamide

Procedure

The captioned compound was synthesized from 3-[(E)-2-(4-chlorophenyl)vinyl]-4-methoxy-benzoic acid and 2-amino-1-methoxybutane in accordance with the same procedure as in the manufacturing method described in step C of Example 1-2-3.

Sources & evidence

ORD record
ord-00e8760e4d9d4dab83c5d59cbae1a3a6
Source dataset
uspto-grants-2011_11
Patent number
US08063046B2

Reaction notes

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