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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 558413Generated: October 28, 2026

2-Aminopropanol → N-(2-hydroxy-1-methyl-ethyl)-4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)-vinyl]-benzamide

https://huagongshe.com/reaction/558413

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-AminopropanolHCID 5126—
Reactant4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acidHCID 23141498—
ProductN-(2-hydroxy-1-methyl-ethyl)-4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)-vinyl]-benzamideHCID 23141445—

Reaction Steps

The captioned compound was synthesized from 4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acid obtained in step B of Example 2-2-1 and (±)-2-amino-1-propanol in accordance with the same procedure as in the methods described in step C of Example 1-2-3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063046B2
Source datasetuspto-grants-2011_11
ORD IDord-dcf53a91537b4f15b910cc55574b587d
Source noteuspto-grants-2011_11