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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 558416Generated: October 30, 2026

4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acid → 4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)-vinyl]-N-((2S,3S)-2,3,4-trihydroxy-butyl)benzamide

https://huagongshe.com/reaction/558416

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acidHCID 23141498—
Reactant(S,S)-4-amino-1,2,3-butanetriolHCID 86590947—
Product4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)-vinyl]-N-((2S,3S)-2,3,4-trihydroxy-butyl)benzamideHCID 59265197—

Reaction Steps

The captioned compound was synthesized from 4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]-benzoic acid obtained in step B of Example 2-2-1 and (2S,3S)-4-amino-1,2,3-butantriol (CAS registry number: 168113-19-7) in accordance with the same procedure as in the methods described in step C of Example 1-2-3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063046B2
Source datasetuspto-grants-2011_11
ORD IDord-d9787067679e47ea9218bbfca4c90759
Source noteuspto-grants-2011_11