HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-formyl-4-methoxybenzoate → 4-methoxy-3-[(E)-2-(4-trifluoromethylphenyl)vinyl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-formyl-4-methoxybenzoate | HCID 638670 | — |
| Reactant | Diethyl 4-(trifluoromethyl)benzylphosphonate | HCID 15819199 | — |
| Reactant | ethyl 4-methoxy-3-[(E)-2-(4-trifluoromethylphenyl)vinyl]-benzoate | HCID 23141481 | — |
| Product | 4-methoxy-3-[(E)-2-(4-trifluoromethylphenyl)vinyl]benzoic acid | HCID 23141489 | — |
Reaction Steps
The captioned compound was synthesized from ethyl 4-methoxy-3-[(E)-2-(4-trifluoromethylphenyl)vinyl]-benzoate, which had been synthesized from diethyl (4-trifluoromethylbenzyl)phosphonate and ethyl 3-formyl-4-methoxybenzoate obtained in step C of Example 1-2-1, in accordance with the same procedure as in the methods described in step B of Example 2-2-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063046B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-9af344e05e8140a5a4c65a517c7f0d86 |
| Source note | uspto-grants-2011_11 |